SEVEN STEPS TO STRATEGIC SDG SENSEMAKING FOR CITIES

Seven Steps to Strategic SDG Sensemaking for Cities

This practitioner paper is based on the need to make sense of UN Agenda 2030 and Sustainable Development Goals (SDGs) at the city level and in an urban context.We examine the need to explain how to utilise the SDGs in strategic, tactical and operative urban development.We find that there are knowledge and practise gaps in how to localise SDGs in th

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Evaluation of Two Novel Hydantoin Derivatives Using Reconstructed Human Skin Model EpiskinTM: Perspectives for Application as Potential Sunscreen Agents

This study aimed to assess two novel 5-arylideneimidazolidine-2,4-dione (hydantoin) derivatives (JH3 and JH10) demonstrating photoprotective Scales activity using the reconstructed human skin model EpiskinTM.The skin permeability, irritation, and phototoxicity of the compounds was evaluated in vitro.Moreover, the in vitro genotoxicity and human met

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AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis

Summary: Doxorubicin induces myocardial injury and fibrosis.Still, no effective interventions are available.AP39 is an H2S donor that explicitly targets mitochondria.This study investigated whether AP39 could Dryer Vent Extension improve doxorubicin-induced myocardial fibrosis.Doxorubicin induced significant myocardial fibrosis while suppressing mi

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